Has Noninvasive Prenatal Testing Impacted Termination of Pregnancy and Live Birth Rates of Infants With Down Syndrome?. Issue 5 (May 2018)

• Record Type: Journal Article
• Authors: Hill, Melissa; Barrett, Angela; Choolani, Mahesh; Lewis, Celine; Fisher, Jane; Chitty, Lyn S.
• Is Part Of: Obstetrical & gynecological survey. Volume 73:Issue 5(2018)
• Publication Date: 2018-05
• Subjects: Obstetrics -- Periodicals; Gynecology -- Periodicals; Generative organs, Female -- Surgery -- Periodicals; 618
• DOI: 10.1097/01.ogx.0000534154.01991.cc
• Languages: English
• ISSNs: 0029-7828

Abstract

Abstract : (Abstracted from Prenat Diagn 2017;37:1281–1290) Noninvasive prenatal testing (NIPT) for aneuploidy using cell-free DNA (cfDNA) has become widely available and popular for detection of Down syndrome (DS) because of its high sensitivity (99%) and specificity (99.5%). The acceptance of NIPT as an alternative to the first-trimester combined test has greatly reduced the use of invasive prenatal diagnostic testing.