Determination of Cu2+ and biothiols by novel red fluorescent hybrid nanoparticles. Issue 22 (22nd May 2018)

• Record Type: Journal Article
• Authors: Zhang, Ling; Wang, Zizhun; Hou, Jiaze; Lei, Lulu; Li, Jiao; Bai, Juan; Huang, Hui; Li, Yongxin
• Is Part Of: Analytical methods. Volume 10:Issue 22(2018)
• Page Start: 2560
• Page End: 2566
• Publication Date: 2018-05-22
• Subjects: Chemistry, Analytic -- Periodicals; Analytical biochemistry -- Periodicals; Chemical laboratories -- Standards -- Periodicals; 543.1905
• DOI: 10.1039/c8ay00614h
• Languages: English
• ISSNs: 1759-9660

Abstract

Abstract : Red fluorescent hybrid nanoparticles (NPG@PFBD) have been designed and synthesized successfully. Abstract : Red fluorescent hybrid nanoparticles (NPG@PFBD) have been designed and synthesized successfully. The NPG@PFBD nanoparticles are composed of a fluorescent semiconducting polymer (PFBD) and n -propyl gallate (NPG). Because of the coordination between the gallate and Cu 2+, Cu 2+ could attach to the hybrid nanoparticles and quench their fluorescence through photoinduced electron transfer (PET). In addition, in the presence of biothiols, such as glutathione (GSH), Cu 2+ would bind to the thiol. The PET between the hybrid nanoparticles and Cu 2+ was weakened, and the fluorescence signal of the nanoparticles was recovered. A facile detection method for Cu 2+ and biothiols was therefore developed. The detection limit for Cu 2+ and GSH was 40 nM and 90 nM, respectively. The proposed fluorescent hybrid nanoparticles have great potential application for Cu 2+ and GSH detection in related biological fields.