Neuroma Prevention: Painful Terminal Neuroma Prevention by Capping PRGD/PDLLA Conduit in Rat Sciatic Nerves (Adv. Sci. 6/2018). Issue 6 (19th June 2018)

• Record Type: Journal Article
• Authors: Yi, Jiling; Jiang, Nan; Li, Binbin; Yan, Qiongjiao; Qiu, Tong; Swaminatha Iyer, Killugudi; Yin, Yixia; Dai, Honglian; Yetisen, Ali K.; Li, Shipu
• Is Part Of: Advanced science. Volume 5:Issue 6(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-06-19
• Subjects: inflammation -- nerve conduits -- neuroma prevention -- painful scar neuropathy -- scar deposition; Science -- Periodicals; 505
• DOI: 10.1002/advs.201870037
• Languages: English
• ISSNs: 2198-3844

Abstract

Abstract : Traumatic neuroma formation results in persistent post‐operative pain after amputation, which reduces quality of life in patients. In article number1700876, Yixia Yin, Honglian Dai, and co‐workers report a method to prevent traumatic neuroma formation after surgery by using a synthetic polymeric capping conduit that can act as a physical barrier to inhibit the invasion of inflammatory infiltration and promote nerve repair.