Vision-related Quality of Life in Patients with Non-infectious Uveitis: A Cross-sectional Study. (4th July 2018)

• Record Type: Journal Article
• Authors: Arriola-Villalobos, Pedro; Abásolo, Lydia; García-Feijoo, Julián; Fernández-Gutiérrez, Benjamín; Méndez-Fernández, Rosalía; Pato, Esperanza; Díaz-Valle, David; Rodriguez-Rodriguez, Luis
• Is Part Of: Ocular immunology and inflammation. Volume 26:Number 5(2018)
• Page Start: 717
• Page End: 725
• Publication Date: 2018-07-04
• Subjects: Cross-sectional study -- ocular comorbidities -- uveitis -- vision-related quality of life -- visual acuity; Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.1080/09273948.2017.1285034
• Languages: English
• ISSNs: 0927-3948

Abstract

ABSTRACT: Purpose : To analyze the influence of socio-demographic, comorbidity, and clinical-related variables in the vision-related quality of life (VR-QoL) of non-infectious uveitis patients. Methods : Cross-sectional study includes 156 consecutive non-infectious uveitis patients from a tertiary uveitis clinic from Madrid (Spain). The main outcome was the log-transformed composite score of the Visual Functioning Questionnaire 25. Bivariate and multivariate ordinary least-squares regression models were performed and results expressed using effect sizes with 95% confidence intervals (95% CI). Results : In the multivariate analysis, one unit increase in the logarithm of the minimum angle of resolution scale [i.e., worse best corrected visual acuity (BCVA)] was associated with a seven times worse VR-QoL (a 0.14-fold change [95% CI: 0.07–0.27]). Patients with ocular comorbidities had a 64% worse VR-QoL (a 0.61-fold change [95% CI: 0.49–0.77]). Conclusions : Lower BCVA and the presence of ocular comorbidities had a significant, independent, and deleterious effect in the VR-QoL of non-infectious uveitis patients.