Fluorimetric and colorimetric analysis of total iron ions in blood or tap water using nitrogen-doped carbon dots with tunable fluorescence. (15th May 2018)

• Record Type: Journal Article
• Authors: Liu, Fengjuan; Jiang, Yao; Fan, Chuan; Zhang, Liyan; Hua, Yue; Zhang, Chunxian; Song, Ning; Kong, Yingjie; Wang, Hua
• Is Part Of: New journal of chemistry. Volume 42:Number 12(2018)
• Page Start: 9676
• Page End: 9683
• Publication Date: 2018-05-15
• Subjects: Chemistry -- Periodicals; Chimie -- Périodiques; 540
• DOI: 10.1039/c8nj00711j
• Languages: English
• ISSNs: 1144-0546

Abstract

Abstract : Nitrogen-doped Cdots were fabricated with tunable blue-green fluorescence and changing of color for fluorimetric and colorimetric assays for total iron. Abstract : Fluorimetric and colorimetric analysis strategies have been developed for simultaneously probing Fe 3+ and Fe 2+ ions in blood or tap water using nitrogen-doped carbon dots (N-Cdots). Herein, the N-Cdots were prepared using melamine by a neutralization heat reaction one-step synthesis route showing high aqueous solubility and environmental stability. Importantly, unlike common carbon dots (Cdots) that generally display one emission of blue fluorescence, they can display excitation-dependent tunable emissions. Moreover, the bright blue-green fluorescence of N-Cdots could be specifically quenched by Fe 3+ or Fe 2+ ions simultaneously, showing a color change. Herein, the fluorescent quenching of N-Cdots is thought to result from the aggregation of N-Cdots triggered by the unique coordination interactions between Fe 3+ or Fe 2+ ions and amine and amide groups of N-Cdots. The developed analysis strategies were employed for the evaluation of the total iron levels in blood or tap water, with a detection limit down to about 5.0 nM, exemplified for Fe 3+ ions. These strategies could be promising for use in practical applications for the clinical diagnosis of iron-relative diseases ( i.e., anemia and cancers) and environmental monitoring of iron pollution. In addition, this one-step neutralization heat reaction route as a facile green synthesis candidate may be tailored for the fabrication of a variety of Cdots, especially those with doped heteroatoms ( i.e., nitrogen) for extensive applications in biomedical and environmental fields.