Controllable synthesis of hollow periodic mesoporous organosilica spheres with radial mesochannels and their degradable behavior. Issue 26 (13th June 2018)

• Record Type: Journal Article
• Authors: Sun, Yangyi; Chen, Min; Wu, Limin
• Is Part Of: Journal of materials chemistry. Volume 6:Issue 26(2018)
• Page Start: 12323
• Page End: 12333
• Publication Date: 2018-06-13
• Subjects: Materials -- Research -- Periodicals; Chemistry, Analytic -- Periodicals; Environmental sciences -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c8ta02569j
• Languages: English
• ISSNs: 2050-7488

Abstract

Abstract : Hollow periodic mesoporous organosilica spheres with radial mesochannels have been efficiently and controllably synthesized only through introducing a pre-hydrolysis process. Abstract : Hollow periodic mesoporous organosilica spheres (HPMOSs) have some important special applications owing to their unique properties, but current syntheses usually involve various template methods that are time-consuming. Herein, we report a highly efficient and controllable synthesis of HPMOSs with radial mesochannels, only through introducing a pre-hydrolysis process to the commercially available bissilylated organosilanes (R′O)3 Si–R–Si(OR′)3 with CTAB. The HPMOSs are robust with a mean diameter as small as 45 nm and a shell thickness as thin as 14 nm. A cytotoxicity assay indicates that the obtained HPMOSs possess good biocompatibility, and the HPMOSs with thioether groups are degradable under a 10 mM glutathione microenvironment. The amphiphilic organosilica precursors derived from the pre-hydrolysis process, CTAB micelles, and ethanol contribute to the formation of the HPMOSs.