Cyclic thrombocytopenia with statistically significant neutrophil oscillations. Issue 7 (31st May 2018)

• Record Type: Journal Article
• Authors: Langlois, Gabriel P.; Arnold, Donald M.; Potts, Jayson; Leber, Brian; Dale, David C.; Mackey, Michael C.
• Is Part Of: Clinical case reports. Volume 6:Issue 7(2018)
• Page Start: 1347
• Page End: 1352
• Publication Date: 2018-05-31
• Subjects: bleeding -- cyclic neutropenia -- cyclic thrombocytopenia -- immune thrombocytopenia -- thrombopoietin; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.1611
• Languages: English
• ISSNs: 2050-0904

Abstract

Key Clinical Message: Cyclic thrombocytopenia is often misdiagnosed as immune thrombocytopenia due to similar clinical features, a fact of significance because cyclic thrombocytopenia generally responds poorly to treatments used successfully in immune thrombocytopenia. A precise diagnosis must establish the statistical significance of periodicity of the platelet counts using statistical methods (eg, Lomb‐Scargle periodogram). Abstract : Cyclic thrombocytopenia is often misdiagnosed as immune thrombocytopenia due to similar clinical features, a fact of significance because cyclic thrombocytopenia generally responds poorly to treatments used successfully in immune thrombocytopenia. A precise diagnosis must establish the statistical significance of periodicity of the platelet counts using statistical methods (eg, Lomb‐Scargle periodogram).