A convenient approach to difluoromethylated all-carbon quaternary centers via Ni(ii)-catalyzed enantioselective Michael addition. Issue 35 (25th May 2018)
- Record Type:
- Journal Article
- Title:
- A convenient approach to difluoromethylated all-carbon quaternary centers via Ni(ii)-catalyzed enantioselective Michael addition. Issue 35 (25th May 2018)
- Main Title:
- A convenient approach to difluoromethylated all-carbon quaternary centers via Ni(ii)-catalyzed enantioselective Michael addition
- Authors:
- Yu, Xuan
Bai, Hui
Wang, Dong
Qin, Zhaohai
Li, Jia-Qi
Fu, Bin - Abstract:
- Abstract : Ni(ii )-catalyzed enantioselective Michael addition afforded compounds with all-carbon quaternary stereogenic centers featuring a CF2 H group in good enantioselectivities. Abstract : A Ni(ii )-catalyzed enantioselective Michael addition of 2-acetyl azarenes with β-difluoromethyl substituted nitroalkenes was successfully realized, which afforded chiral CF2 H-containing compounds in good enantioselectivities (up to 93% ee ). This protocol provides a new convenient approach to all-carbon quaternary stereogenic centers featuring a CF2 H group.
- Is Part Of:
- RSC advances. Volume 8:Issue 35(2018)
- Journal:
- RSC advances
- Issue:
- Volume 8:Issue 35(2018)
- Issue Display:
- Volume 8, Issue 35 (2018)
- Year:
- 2018
- Volume:
- 8
- Issue:
- 35
- Issue Sort Value:
- 2018-0008-0035-0000
- Page Start:
- 19402
- Page End:
- 19408
- Publication Date:
- 2018-05-25
- Subjects:
- Chemistry -- Periodicals
540.5 - Journal URLs:
- http://pubs.rsc.org/en/Journals/JournalIssues/RA ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c8ra02853b ↗
- Languages:
- English
- ISSNs:
- 2046-2069
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8036.750300
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 6866.xml