In vivo and in vitro identification of Z-BOX C – a new bilirubin oxidation end product. Issue 19 (13th March 2018)

• Record Type: Journal Article
• Authors: Ritter, Marcel; Neupane, Sandesh; Seidel, Raphael A.; Steinbeck, Christoph; Pohnert, Georg
• Is Part Of: Organic & biomolecular chemistry. Volume 16:Issue 19(2018)
• Page Start: 3553
• Page End: 3555
• Publication Date: 2018-03-13
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c8ob00164b
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : A new bilirubin degradation end product was isolated and characterized. Abstract : A new bilirubin oxidation end product (BOX) was isolated and characterized. The formation of the so-called Z -BOX C proceeds from bilirubin via propentdyopents as intermediates. This BOX was detected in pathological human bile samples using liquid chromatography/mass spectrometry and has potential relevance for liver dysfunction and cerebral vasospasms.