Α, β-Diaryl unsaturated ketones via palladium-catalyzed ring-opening of cyclopropenones with organoboronic acids. Issue 10 (4th April 2018)

• Record Type: Journal Article
• Authors: Shan, Lidong; Wu, Ge; Liu, Miaochang; Gao, Wenxia; Ding, Jinchang; Huang, Xiaobo; Wu, Huayue
• Is Part Of: Organic chemistry frontiers. Volume 5:Issue 10(2018)
• Page Start: 1651
• Page End: 1654
• Publication Date: 2018-04-04
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/c8qo00241j
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : Palladium-catalyzed ring-opening acylation of cyclopropenones with organoboronic acids (aryl and vinylboronic acids) at room temperature has been developed to synthesise α, β-diaryl unsaturated ketones with good yields and excellent stereospecificity. Abstract : Palladium-catalyzed ring-opening acylation of cyclopropenones with organoboronic acids at room temperature has been developed. Both arylboronic acids and vinylboronic acids are viable in this acylation reaction, providing a new protocol to synthesise α, β-diaryl unsaturated ketones with good yields and excellent stereospecificity. Preliminary mechanistic studies indicated that a vinylpalladium intermediate was generated in this procedure.