A simplified method to account for wall motion in patient-specific blood flow simulations of aortic dissection: Comparison with fluid-structure interaction. (August 2018)

• Record Type: Journal Article
• Authors: Bonfanti, Mirko; Balabani, Stavroula; Alimohammadi, Mona; Agu, Obiekezie; Homer-Vanniasinkam, Shervanthi; Díaz-Zuccarini, Vanessa
• Is Part Of: Medical engineering & physics. Volume 58(2018)
• Page Start: 72
• Page End: 79
• Publication Date: 2018-08
• Subjects: Computational fluid dynamics (CFD) -- Fluid-structure interaction (FSI) -- Aortic dissection -- Compliant model -- Windkessel model -- Blood flow -- Moving boundary; Biomedical engineering -- Periodicals; Biomedical Engineering -- Periodicals; Physics -- Periodicals; Génie biomédical -- Périodiques; Biomedical engineering; Electronic journals; Periodicals; 610.28
• DOI: 10.1016/j.medengphy.2018.04.014
• Languages: English
• ISSNs: 1350-4533

Abstract

Highlights: A simplified method to account for wall motion in blood flow simulations is proposed. An aortic dissection case is studied and results are compared against FSI. Wall-motion effects on flow are accurately captured at less computational cost. Patient-specific simulations tuned with imaging data (e.g. MRI) possible. Proposed approach is a promising alternative to FSI for patient-specific models. Abstract: Aortic dissection (AD) is a complex and highly patient-specific vascular condition difficult to treat. Computational fluid dynamics (CFD) can aid the medical management of this pathology, yet its modelling and simulation are challenging. One aspect usually disregarded when modelling AD is the motion of the vessel wall, which has been shown to significantly impact simulation results. Fluid-structure interaction (FSI) methods are difficult to implement and are subject to assumptions regarding the mechanical properties of the vessel wall, which cannot be retrieved non-invasively. This paper presents a simplified 'moving-boundary method' (MBM) to account for the motion of the vessel wall in type-B AD CFD simulations, which can be tuned with non-invasive clinical images (e.g. 2D cine-MRI). The method is firstly validated against the 1D solution of flow through an elastic straight tube; it is then applied to a type-B AD case study and the results are compared to a state-of-the-art, full FSI simulation. Results show that the proposed method can capture the main effects due to the wall motion on the flow field: the average relative difference between flow and pressure waves obtained with the FSI and MBM simulations was less than 1.8% and 1.3%, respectively and the wall shear stress indices were found to have a similar distribution. Moreover, compared to FSI, MBM has the advantage to be less computationally expensive (requiring half of the time of an FSI simulation) and easier to implement, which are important requirements for clinical translation.