Catalytic alkenylation of γ-substituted butenolides with cyclic N-sulfonylated imines in water leading to α-arylidene butenolide derivatives. Issue 31 (1st August 2018)

• Record Type: Journal Article
• Authors: Li, Feng; Wang, Jingjing; Pei, Wenlong; Ma, Hai; Li, Hong; Cui, Mingyue; Peng, Shuxin; Wang, Shihui; Liu, Lantao
• Is Part Of: Tetrahedron letters. Volume 59:Issue 31(2018)
• Page Start: 3010
• Page End: 3014
• Publication Date: 2018-08-01
• Subjects: γ-Substituted butenolides -- Cyclic N-sulfonylated imines -- Alkenylation -- In water; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2018.06.062
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: The development of mild and atom-economical protocols to access structurally diverse alkenes is still highly desirable. The Et3 N-catalyzed alkenylation of γ-substituted butenolides with cyclic N -sulfonylated imines in water is described. The reaction is efficient under mild conditions to give α-arylidene butenolide derivatives in high yield (82–96%). Abstract: An efficient Et3 N-catalyzed alkenylation of γ-substituted deconjugated butenolides with cyclic N -sulfonylated imines in water is described. The reaction proceeds efficiently under mild reaction conditions to give α-arylidene butenolide derivatives in high yield (82–96%).