A new bischromanone from the stems of Semecarpus caudata. Issue 15 (3rd August 2018)

• Record Type: Journal Article
• Authors: Dang, Phu H.; Nguyen, Tinh T.; Le, Tho H.; Nguyen, Hai X.; Nguyen, Mai T. T.; Nguyen, Nhan T.
• Is Part Of: Natural product research. Volume 32:Issue 15(2018)
• Page Start: 1745
• Page End: 1750
• Publication Date: 2018-08-03
• Subjects: Semecarpus caudata -- Anacardiaceae -- bischromanone -- tyrosinase inhibitory; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2017.1399391
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: From an CHCl3 -soluble fraction of the stems of Semecarpus caudata, one new bischromanone named semecarpanone (1 ), together with 5 known flavonoids (2 –6 ) were isolated. Their structures were elucidated based on interpretation of spectroscopic data. The stereo-configuration of1 was identified based on the calculated and experimental coupling constants. Compounds4 –6 showed potent tyrosinase inhibitory activity with the IC50 values ranging from 15.0 to 76.3 μM. Abstract :