Occurrence of aflatoxin M1 in milk samples from Italy analysed by online-SPE UHPLC-MS/MS. Issue 15 (3rd August 2018)

• Record Type: Journal Article
• Authors: Campone, Luca; Piccinelli, Anna Lisa; Celano, Rita; Pagano, Imma; Di Sanzo, Rosa; Carabetta, Sonia; Russo, Mariateresa; Rastrelli, Luca
• Is Part Of: Natural product research. Volume 32:Issue 15(2018)
• Page Start: 1803
• Page End: 1808
• Publication Date: 2018-08-03
• Subjects: Aflatoxin M1 -- mycotoxin analysis -- on-line SPE -- occurrence of aflatoxin M1 -- milk and milk samples; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2017.1402327
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: The occurrence of aflatoxin M1 in 69 milk samples collected in a south region of Italy in 2016 was evaluated. The samples were analysed using an automated method based on online SPE coupled with UHPLC tandem mass spectrometry. After a salt induced liquid–liquid extraction with acetonitrile to remove protein from milk, the extract was diluted with water and analysed using an automated online SPE MS/MS method. Among the analysed samples no one had AFM1 higher than the legally allowable limits whereas 71.4% of the other analysed samples were above the LOD of the method. The highest contamination level of AFM1 was found in pasteurised milk (44.39 ng kg −1 ). The results show the worrying and widespread of AFM1 contamination, highlighting the necessity of monitoring studies in order to evaluate the reduction of the maximum legal limit. Abstract :