Rapid detection and monitoring of human coronavirus infections. (July 2018)

• Record Type: Journal Article
• Authors: Bruning, A.H.L.; Aatola, H.; Toivola, H.; Ikonen, N.; Savolainen-Kopra, C.; Blomqvist, S.; Pajkrt, D.; Wolthers, K.C.; Koskinen, J.O.
• Is Part Of: New microbes and new infections. Volume 24(2018)
• Page Start: 52
• Page End: 55
• Publication Date: 2018-07
• Subjects: Human coronavirus -- point-of-care test -- rapid antigen test -- rapid detection -- respiratory tract infection; Medical microbiology -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; Microbiology -- Periodicals; Communicable Diseases -- Periodicals; Infection -- Periodicals; 616.9041
• DOI: 10.1016/j.nmni.2018.04.007
• Languages: English
• ISSNs: 2052-2975

Abstract

Abstract: Human coronaviruses (CoVs) are increasingly recognized as important respiratory pathogens associated with a broad range of clinical diseases. We sought to increase the insight into clinically relevant CoV infections by monitoring antigen concentrations in six confirmed CoV-positive patients using a newly developed assay for rapid detection of CoV OC43 infections. Antigen positivity lasted 3 to 6 days in secondary infections and 13 days in primary infection. CoV infections are clinically diverse, are common, and cannot be diagnosed from clinical symptoms alone.