Cutaneous ulcerations caused by Paecilomyces variotii in a renal transplant recipient. Issue 3 (31st March 2018)

• Record Type: Journal Article
• Authors: Eren, Davut; Eroglu, Eray; Ulu Kilic, Aysegul; Atalay, Mustafa Altay; Mumcu, Necati; Sipahioglu, Murat Hayri; Canoz, Ozlem; Koc, Ayse Nedret; Oymak, Oktay
• Is Part Of: Transplant infectious disease. Volume 20:Issue 3(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-03-31
• Subjects: fungal infection -- immunosuppression -- Paecilomyces variotii -- transplantation; Transplantation of organs, tissues, etc -- Complications -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 617.01
• DOI: 10.1111/tid.12871
• Languages: English
• ISSNs: 1398-2273

Abstract

Abstract: Skin infections caused by Paecilomyces species have been rarely described in patients with solid organ transplantation. Cutaneous manifestations are highly variable and include erythematous macules, nodules, pustules, and vesicular and necrotic lesions. The diagnosis of these infections is generally made by examination of a skin biopsy. Management of these fungal infections is difficult due to the immunocompromised state of the patients. Moreover, antifungal therapy and immunosuppressive drug interactions should be considered during treatment management. Herein, we reported a case of cellulitis caused by Paecilomyces variotii in a 56‐year‐old man who had undergone a kidney transplantation. Erythematous macular and nodular lesions on the left hand and left foot appeared first; within 2 months the skin lesions became ulcerated, hemorrhagic, and progressively painful and the patient was admitted to our hospital. The diagnosis was made by skin biopsy and tissue culture. The skin lesions resolved by the sixth week of the treatment with voriconazole.