Sacrifice and extracranial reconstruction of the common or internal carotid artery in advanced head and neck carcinoma: Review and meta‐analysis. Issue 6 (5th February 2018)

• Record Type: Journal Article
• Authors: Bäck, Leif J. J.; Aro, Katri; Tapiovaara, Laura; Vikatmaa, Pirkka; de Bree, Remco; Fernández‐Álvarez, Verónica; Kowalski, Luiz P.; Nixon, Iain J.; Rinaldo, Alessandra; Rodrigo, Juan P.; Robbins, K. Thomas; Silver, Carl E.; Snyderman, Carl H.; Suárez, Carlos; Takes, Robert P.; Ferlito, Alfio
• Is Part Of: Head & neck. Volume 40:Issue 6(2018)
• Page Start: 1305
• Page End: 1320
• Publication Date: 2018-02-05
• Subjects: carotid artery -- complications -- head and neck cancer -- reconstruction -- survival; Head -- Diseases -- Periodicals; Neck -- Diseases -- Periodicals; Head -- Periodicals; Neck -- Periodicals; Face -- Periodicals; 617.51059
• DOI: 10.1002/hed.25093
• Languages: English
• ISSNs: 1043-3074

Abstract

Abstract: Background: Sacrifice and reconstruction of the carotid artery in cases of head and neck carcinoma with invasion of the common or internal carotid artery is debated. Methods: We conducted a systematic search of electronic databases and provide a review and meta‐analysis. Results: Of the 72 articles identified, 24 met the inclusion criteria resulting in the inclusion of 357 patients. The overall perioperative 30‐day mortality was 3.6% (13/357). Permanent cerebrovascular complications occurred in 3.6% (13/357). Carotid blowout episodes were encountered in 1.4% (5/357). The meta‐regression analysis showed a significant difference in 1‐year overall survival between reports published from 1981‐1999 (37.0%) and 2001‐2016 (65.4%; P = .02). Conclusion: This review provides evidence that sacrifice with extracranial reconstruction of common or internal carotid artery in selected patients with head and neck carcinoma may improve survival with acceptable complication rates. However, all of the published literature is retrospective involving selected series and, therefore, precludes determining the absolute effectiveness of the surgery.