Biomimicry Model: Mechanobiological Mimicry of Helper T Lymphocytes to Evaluate Cell–Biomaterials Crosstalk (Adv. Mater. 23/2018). Issue 23 (1st June 2018)

• Record Type: Journal Article
• Authors: Hasani‐Sadrabadi, Mohammad Mahdi; Majedi, Fatemeh S.; Bensinger, Steven J.; Wu, Benjamin M.; Bouchard, Louis‐S.; Weiss, Paul S.; Moshaverinia, Alireza
• Is Part Of: Advanced materials. Volume 30:Issue 23(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-06-01
• Subjects: artificial immune cell -- controlled release -- cytokine delivery -- hydrogel microparticle; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201870159
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : Super‐soft functional microparticles mimic the mechanobiological features of T cells. These particles can penetrate 3D microenvironments, have prolonged blood circulation, and can release various cytokines on demand. A biomimetic model presented by Louis‐S. Bouchard, Paul S. Weiss, Alireza Moshaverinia, and co‐workers in article number1706780 enables optimization of the design parameters required for the engineering of more efficient drug carriers and serves as a potent replica for understanding the mechanical behavior of immune cells.