Cancer Immunotherapy: PD‐1 Blockade Cellular Vesicles for Cancer Immunotherapy (Adv. Mater. 22/2018). Issue 22 (May 2018)

• Record Type: Journal Article
• Authors: Zhang, Xudong; Wang, Chao; Wang, Jinqiang; Hu, Quanyin; Langworthy, Benjamin; Ye, Yanqi; Sun, Wujin; Lin, Jing; Wang, Tianfu; Fine, Jason; Cheng, Hao; Dotti, Gianpietro; Huang, Peng; Gu, Zhen
• Is Part Of: Advanced materials. Volume 30:Issue 22(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-05
• Subjects: cancer immunotherapy -- cell therapy -- drug delivery -- immune checkpoint blockade -- nanomedicine; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201870152
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : In article number1707112, Peng Huang, Zhen Gu, and co‐workers engineer cellular nanovesicles presenting PD‐1 receptors on their membranes, which enhance antitumor response by disrupting the PD‐1/PD‐L1 immune inhibitory axis. These nanovesicles could also be adapted to carry a variety of therapeutics to achieve synergistic cancer therapy.