A randomised controlled trial of consumption of dark chocolate in pregnancy to reduce pre‐eclampsia: Difficulties in recruitment, allocation and adherence. (15th September 2017)

• Record Type: Journal Article
• Authors: Gnanendran, Subashini; Porrett, Jemma; Woods, Cindy; Buttrose, Maryke; Jukka, Clare; Hollins, Jane; Robson, Stephen; de Costa, Caroline
• Is Part Of: Australian and New Zealand journal of obstetrics and gynaecology. Volume 58:Number 3(2018)
• Page Start: 358
• Page End: 361
• Publication Date: 2017-09-15
• Subjects: dark chocolate -- dark chocolate in pregnancy -- flavonoid rich dark chocolate -- pre‐eclampsia; Obstetrics -- Periodicals; Gynecology -- Periodicals; 618.05
• DOI: 10.1111/ajo.12694
• Languages: English
• ISSNs: 0004-8666

Abstract

Abstract : In 2013–2014 we undertook a randomised controlled trial (RCT) to determine whether the daily ingestion of dark chocolate during pregnancy could reduce the incidence of pre‐eclampsia in primigravidae. However, after two years we had not succeeded in recruiting more than 3.5% of the number of participants required to answer the research question, and the trial was halted. We also reviewed the literature on this topic and found it to be limited. We report here our findings and discuss the difficulties facing researchers in this area.