The promising potentials of capped gold nanoparticles for drug delivery systems. (9th August 2018)

• Record Type: Journal Article
• Authors: Khoshnevisan, Kamyar; Daneshpour, Maryam; Barkhi, Mohammad; Gholami, Morteza; Samadian, Hadi; Maleki, Hassan
• Is Part Of: Journal of drug targeting. Volume 26:Number 7(2018)
• Page Start: 525
• Page End: 532
• Publication Date: 2018-08-09
• Subjects: Capped gold nanoparticles -- reducing agent -- drug delivery systems -- anticancer drug -- cancer therapy; Drug delivery systems -- Periodicals; Drug Delivery Systems; Vehicles; Drug Administration Routes; Drug Evaluation; 615.7
• DOI: 10.1080/1061186X.2017.1387790
• Languages: English
• ISSNs: 1061-186X

Abstract

Abstract: Fabrication and characterisation of gold nanoparticles (GNPs) through reducing agents and different capped agents are one of their most attractive applications in biomedicine. GNPs are coated using various agents such as carbohydrate, amino acids, peptides and proteins. These capped gold nanoparticles (C-GNPs) are applied for wide different applications including drug delivery in the recent decade and potential treatment and diagnosis in drug delivery systems (DDS). Recent studies have shown that these novel compounds and conjugated-nanoparticles drugs play a key role for the promising cure of high-risk refractory diseases. In addition, it seems that these compounds have a capability for potential treatment of certain cancers. In this review, a well-defined description of C-GNPs and the application of these nanoparticles are discussed. Our study revealed that C-GNPs with anticancer drugs or new compounds could be potentially applied for biomedical usage especially in cancer therapy.