Photodynamic Therapy: Porous Porphyrin‐Based Organosilica Nanoparticles for NIR Two‐Photon Photodynamic Therapy and Gene Delivery in Zebrafish (Adv. Funct. Mater. 21/2018). (May 2018)

• Record Type: Journal Article
• Authors: Mauriello Jimenez, Chiara; Aggad, Dina; Croissant, Jonas G.; Tresfield, Karen; Laurencin, Danielle; Berthomieu, Dorothée; Cubedo, Nicolas; Rossel, Mireille; Alsaiari, Shahad; Anjum, Dalaver H.; Sougrat, Rachid; Roldan‐Gutierrez, Manuel A.; Richeter, Sébastien; Oliviero, Erwan; Raehm, Laurence; Charnay, Clarence; Cattoën, Xavier; Clément, Sébastien; Wong Chi Man, Michel; Maynadier, Marie; Chaleix, Vincent; Sol, Vincent; Garcia, Marcel; Gary‐Bobo, Magali; Khashab, Niveen M.; Bettache, Nadir; Durand, Jean‐Olivier
• Is Part Of: Advanced functional materials. Volume 28:Number 21(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-05
• Subjects: nucleic acid delivery -- organosilica nanoparticles -- porphyrins -- two‐photon photodynamic therapy -- zebrafish embryos; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.201870143
• Languages: English
• ISSNs: 1616-301X

Abstract

Abstract : Porphyrin‐based mesoporous organosilica nanoparticles are designed by Nadir Bettache, Jean‐Olivier Durand, and co‐workers in article number1800235 . These nanoparticles possess a high specific surface area and large mesopores of 10–80 nm diameters. Two‐photon photodynamic therapy of breast cancer and siRNA delivery were both performed in zebrafish embryos and were very efficient.