Cardiac abnormalities in Parkinson's disease and Parkinsonism. (July 2018)

• Record Type: Journal Article
• Authors: Scorza, Fulvio A.; Fiorini, Ana C.; Scorza, Carla A.; Finsterer, Josef
• Is Part Of: Journal of clinical neuroscience. Volume 53(2018)
• Page Start: 1
• Page End: 5
• Publication Date: 2018-07
• Subjects: Parkinson -- Autonomic dysfunction -- Cardiac disease -- Cardiomyopathy -- Cardiac involvement -- Arrhythmias -- Sudden cardiac death; Brain -- Surgery -- Periodicals; Neurosciences -- Periodicals; Nervous system -- Surgery -- Periodicals; Brain -- surgery -- Periodicals; Neurosurgical Procedures -- Periodicals; Neurosciences -- Periodicals; Electronic journals; 616.8
• DOI: 10.1016/j.jocn.2018.04.031
• Languages: English
• ISSNs: 0967-5868

Abstract

Highlights: The most prominent cardiac abnormality found in PD/PS patients is cardiac autonomic dysfunction. The frequency of coronary heart disease in PD is a matter of debate. Only rarely reported in PD/PS are cardiomyopathies, arrhythmias, and sudden cardiac death, and SUDPAR. Early recognition of cardiac involvement is important for preventing SCD and SUDPAR. Abstract: Objectives: Though there is increasing evidence for primary cardiac disease in Parkinson's disease (PD) and Parkinsonism (PS), this evidence is hardly included in the general management of these patients. Methods: Literature review. Results: PD is one of the most common age-related neurodegenerative disorders. Epidemiological studies have shown that PD is accompanied by high rates of premature death compared with the general population. In general, death in PD/PS is usually caused by determinant factors such as pneumonia, cerebrovascular, and cardiovascular disease. There is a significant body of literature demonstrating involvement of the heart in PD/PS. Cardiac involvement in PD/PS includes cardiac autonomic dysfunction, cardiomyopathy, coronary heart disease, arrhythmias, conduction defects, and sudden cardiac death (SCD), and sudden unexpected death in Parkinson's disease (SUDPAR). Conclusions: Cardiac abnormalities found in PD/PS are manifold but the most prominent is cardiac autonomic dysfunction. The frequency of coronary heart disease in PD is a matter of debate. Only rarely reported in PD/PS are cardiomyopathies, arrhythmias, and sudden cardiac death, and SUDPAR. It is particularly recommended that PD/PS patients are more intensively investigated cardiologically as soon as the diagnosis is established. Early recognition of cardiac involvement is important for preventing SCD and SUDPAR.