Paradoxical immune reconstitution inflammatory syndrome associated with disseminated tuberculosis infection in an unrelated donor cord blood transplant recipient. Issue 3 (3rd April 2018)

• Record Type: Journal Article
• Authors: Lee, Yeon Joo; Bacchus, Melissa; Schmidt, Elizabeth; Chawla, Mohit; Barker, Juliet N.; Papanicolaou, Genovefa A.
• Is Part Of: Transplant infectious disease. Volume 20:Issue 3(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-04-03
• Subjects: hematopoietic cell transplant -- immune reconstitution inflammatory syndrome -- tuberculosis; Transplantation of organs, tissues, etc -- Complications -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 617.01
• DOI: 10.1111/tid.12889
• Languages: English
• ISSNs: 1398-2273

Abstract

Abstract: Tuberculosis (TB) is an infrequent infection after hematopoietic cell transplant (HCT), with associated mortality up to 30%. The utility of universal screening for latent TB in HCT candidates is controversial due to the lack of sensitive screening tests. We describe a case of disseminated TB infection complicated by immune reconstitution inflammatory syndrome in an adult double unit umbilical cord blood transplant recipient who originated from the United Arab Emirates.