Screening recipients of increased risk donor organs: A multicenter retrospective study. Issue 3 (26th March 2018)

• Record Type: Journal Article
• Authors: Ison, Michael G.; Rana, Meenakshi M.; Brizendine, Kyle D.; Chimienti, Sonia; Le, Jade; Kfoury, Rosette; Mohazabnia, Parvin; Theodoropoulos, Nicole
• Is Part Of: Transplant infectious disease. Volume 20:Issue 3(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-03-26
• Subjects: hepatitis B -- hepatitis C -- HIV -- organ recipients -- PHS increased risk donors -- screening; Transplantation of organs, tissues, etc -- Complications -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 617.01
• DOI: 10.1111/tid.12862
• Languages: English
• ISSNs: 1398-2273

Abstract

Abstract: Organ Procurement & Transplantation Network policy requires post‐transplant screening of recipients of organs from donors at increased risk for transmission of HIV, hepatitis B virus, and hepatitis C virus. Available data suggest that follow‐up testing of recipients is not routinely conducted. Data on increased risk donors and recipients of their organs from 2008 to 2012 were retrospectively collected from 6 transplant centers after IRB approval. Descriptive statistics were performed. About 363 (60%) recipients were screened for transmission of HIV, HBV, and/or HCV at some time point; 257 (70.8%) within 90 days of transplant. The type of test used to screen for infection was variable with many recipients (25%‐43%) screened with serology alone. Our results reveal that post‐transplant screening for HIV, HBV, and HCV in recipients of increased risk donor organs did not universally occur and testing methods were variable.