The Modalities of Nonadherence to Highly Active Antiretroviral Therapy and the Associated Factors Related to Patients' Sociodemographic Characteristics and Their Caregiving Perceptions in Ouagadougou (Burkina Faso). (May 2016)

• Record Type: Journal Article
• Authors: Guira, Oumar; Kaboré, Delwendé S. R.; Dao, Ginette; Zagré, Nicaise; Zohoncon, Théodora M.; Pietra, Virginio; Drabo, Joseph Y.; Simporé, Jacques
• Is Part Of: Journal of the International Association of Providers of AIDS Care. Volume 15:Number 3(2016:May/Jun.)
• Page Start: 256
• Page End: 260
• Publication Date: 2016-05
• Subjects: HIV/AIDS -- nonadherence -- HAART -- Burkina Faso; AIDS (Disease) -- Periodicals; 616.9792
• DOI: 10.1177/2325957415616492
• Languages: English
• ISSNs: 2325-9574

Abstract

Background: The authors studied the modalities of nonadherence to highly active antiretroviral therapy (HAART) and its sociodemographic associated factors and those in relation to caregiving perception in Ouagadougou. Methods: A cross-sectional study was performed from December 2013 to February 2014 in 2 health centers. Adults receiving HAART for at least 3 months were included. Adherence was studied according to the quantitative, qualitative, and global criteria. Factors associated with nonadherence were analyzed with chi-square and Fisher tests. A logistic regression model was applied for multivariate analysis. Results: The authors studied 152 patients: mean age 40.7 ± 7.8 years and sex ratio 0.34. Frequencies were 7.2% for self-reported quantitative, 20.4% for calculated quantitative, 31.6% for qualitative, and 38.2% for global nonadherence. Married status ( P = .02), patient's dissatisfaction regarding clinical monitoring ( P = .01), and therapeutic education ( P = .03) were associated with nonadherence. In multivariate analysis, married status remains associated (odds ratio = 7.00, 95% confidence interval = 1.89-25.8, P = .0004). Conclusion: Nonadherence to HAART needs to be correctly managed during HIV/AIDS monitoring.