Is Celiac Disease an Etiological Factor in Children With Migraine?. (June 2016)

• Record Type: Journal Article
• Authors: Balcı, Oya; Yılmaz, Deniz; Sezer, Taner; Hızlı, Şamil
• Is Part Of: Journal of child neurology. Volume 31:Number 7(2016:Jul.)
• Page Start: 929
• Page End: 931
• Publication Date: 2016-06
• Subjects: migraine -- celiac disease -- children; Nervous system -- Diseases -- Periodicals; 618.928
• DOI: 10.1177/0883073816630088
• Languages: English
• ISSNs: 0883-0738

Abstract

To determine the prevalence of celiac disease in children and adolescents with migraine, the authors investigated serum levels of tissue transglutaminase antibody immunoglobulin A and total immunoglobulin A from 81 children with migraine and in a healthy control group of 176 children. Study participants who were positive for tissue transglutaminase immunoglobulin A antibodies underwent a duodenal biopsy. Two patients in the migraine group (2.5%) and 1 in the control group (0.57%) tested positive for serum tissue transglutaminase immunoglobulin A antibodies ( P > .05). Duodenal biopsy did not confirm celiac disease in both groups, and these patients were considered "potential celiac" cases. In the present study, children with migraine did not exhibit a higher prevalence rate of celiac disease compared with healthy controls. Therefore, the screening test for celiac disease is not a necessary part of the management of migraine in children.