Vitamin D supplementation may improve symptoms in Meniere's disease. (July 2018)

• Record Type: Journal Article
• Authors: Büki, Bela; Jünger, Heinz; Lundberg, Yunxia Wang
• Is Part Of: Medical hypotheses. Volume 116(2018)
• Page Start: 44
• Page End: 46
• Publication Date: 2018-07
• Subjects: Vitamin D -- Deficiency -- Meniere's disease; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Medicine; Periodicals; 610
• DOI: 10.1016/j.mehy.2018.04.019
• Languages: English
• ISSNs: 0306-9877

Abstract

Abstract: In the last 4 years the authors observed a trend that correcting vitamin D deficiency in newly diagnosed cases of Meniere's disease decreased the necessity of the ablative therapy with intratympanic gentamicin. According to their hypothesis, vitamin D supplementation may indeed have a beneficial effect in Meniere's disease if the symptoms are caused by a local postviral autoimmune reaction. Vitamin D has a strong immunomodulatory role, one of which is the regulation of the expression of pro-inflammatory mediators. The authors suggest further epidemiological studies to decide if there is a connection between vitamin D deficiency and Meniere's disease.