Effect of a Tibetan herbal mixture on microvascular endothelial function, heart rate variability and biomarkers of inflammation, clotting and coagulation. (August 2015)

• Record Type: Journal Article
• Authors: Schäfer, Daniela; Lambrecht, Julia; Radtke, Thomas; Wilhelm, Matthias; Saner, Hugo
• Is Part Of: European journal of preventive cardiology. Volume 22:Number 8(2015)
• Page Start: 1043
• Page End: 1045
• Publication Date: 2015-08
• Subjects: Padma 28 -- coronary artery disease -- microvascular endothelial function -- EndoPat -- autonomic nervous tone -- biomarkers; Cardiovascular system -- Diseases -- Prevention -- Periodicals; Cardiac patients -- Rehabilitation -- Periodicals; 616.12
• DOI: 10.1177/2047487314544985
• Languages: English
• ISSNs: 2047-4873

Abstract

In this 6-week prospective, randomized, placebo-controlled and double-blind study, we investigated the effects of a natural herbal remedy based on a recipe from Tibet (Padma® 28), on microvascular endothelial function, heart rate variability and biomarkers of inflammation, clotting and coagulation in 80 coronary artery disease (CAD) patients (age 66 ± 8 years) on guideline-based medication for secondary prevention. We found no significant effects of Padma 28 and conclude that the addition of Padma 28 to guideline-based secondary prevention treatment of CAD did not lead to significant effects on important surrogate markers in elderly male CAD patients.