Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder: Section 6. Special Populations: Youth, Women, and the Elderly. (September 2016)

• Record Type: Journal Article
• Authors: MacQueen, Glenda M.; Frey, Benicio N.; Ismail, Zahinoor; Jaworska, Natalia; Steiner, Meir; Lieshout, Ryan J. Van; Kennedy, Sidney H.; Lam, Raymond W.; Milev, Roumen V.; Parikh, Sagar V.; Ravindran, Arun V.
• Is Part Of: Canadian journal of psychiatry =. Volume 61:Number 9(2016)
• Page Start: 588
• Page End: 603
• Publication Date: 2016-09
• Subjects: major depressive disorder -- clinical practice guidelines -- evidence-based medicine -- meta-analysis -- child and adolescent psychiatry -- geriatric psychiatry -- maternal health -- perinatal -- postpartum -- systematic reviews; Psychiatry -- Periodicals; Psychiatry -- Canada -- Periodicals; 616.8900971
• DOI: 10.1177/0706743716659276
• Languages: English
• ISSNs: 0706-7437

Abstract

Background: The Canadian Network for Mood and Anxiety Treatments (CANMAT) conducted a revision of the 2009 guidelines by updating the evidence and recommendations. The scope of the 2016 guidelines remains the management of major depressive disorder (MDD) in adults, with a target audience of psychiatrists and other mental health professionals. Methods: Using the question-answer format, we conducted a systematic literature search focusing on systematic reviews and meta-analyses. Evidence was graded using CANMAT-defined criteria for level of evidence. Recommendations for lines of treatment were based on the quality of evidence and clinical expert consensus. This section on "Special Populations" is the sixth of six guidelines articles. Results: Recent studies inform the treatment of MDD in children and adolescents, pregnant and breastfeeding women, women in perimenopause or menopause, and the elderly. Evidence for efficacy of treatments in these populations is more limited than for the general adult population, however, and risks of treatment in these groups are often poorly studied and reported. Conclusions: Despite the limited evidence base, extant data and clinical experience suggest that each of these special populations can benefit from the systematic application of treatment guidelines for treatment of MDD.