Pulmonary tumor thrombotic microangiopathy caused by prostate carcinoma. (August 2016)

• Record Type: Journal Article
• Authors: Katayama, Daisuke; Kuriyama, Keiko; Kinoshita, Tatsuya; Nagai, Keisuke; Hongyo, Hidenari; Kishimoto, Kentaro; Inoue, Atsuo; Takamura, Manabu; Choi, Soomi
• Is Part Of: Acta radiologica open. Volume 5:Number 8(2016)
• Publication Date: 2016-08
• Subjects: Prostate -- adenocarcinoma -- autopsy -- lung – pathology -- hypertension -- pulmonary – etiology -- thrombotic microangiopathies – complications; Radiology -- Periodicals; Diagnostic Imaging -- Periodicals; Radiology; Periodicals; 616.075705
• DOI: 10.1177/2058460116662300
• Languages: English
• ISSNs: 2058-4601

Abstract

Pulmonary tumor thrombotic microangiopathy (PTTM) is a fatal malignancy-related condition that involves rapidly progressing hypoxia and pulmonary hypertension. We report a case of PTTM caused by prostate carcinoma, which was diagnosed before autopsy in an 81-year-old man. Computed tomography showed diffuse ground-glass opacities, consolidation, and small nodules in the peripheral regions of the lung. Autopsy showed adenocarcinoma cells embolizing small pulmonary arteries with fibrocellular intimal proliferation, which was consistent with PTTM caused by prostate carcinoma.