Institution-wide and Within-Patient Evolution of Daptomycin Susceptibility in Vancomycin-Resistant Enterococcus faecium Bloodstream Infections. (14th January 2018)

• Record Type: Journal Article
• Authors: Woods, Robert J.; Patel, Twisha S.; Nagel, Jerod L.; Newton, Duane W.; Read, Andrew F.
• Is Part Of: Infection control and hospital epidemiology. Volume 39:Number 2(2018)
• Page Start: 226
• Page End: 228
• Publication Date: 2018-01-14
• Subjects: Nosocomial infections -- Epidemiology -- Periodicals; Health facilities -- Sanitation -- Periodicals; Hospital buildings -- Sanitation -- Periodicals; Cross Infection -- Periodicals; Epidemiology -- Periodicals; Hospitals -- Periodicals; Infection Control -- Periodicals; 614.44
• DOI: 10.1017/ice.2017.279
• Languages: English
• ISSNs: 0899-823X

Abstract

Abstract : We report daptomycin minimum inhibitory concentrations (MICs) for vancomycin-resistant Enterococcus faecium isolated from bloodstream infections over a 4-year period. The daptomycin MIC increased over time hospital-wide for initial isolates and increased over time within patients, culminating in 40% of patients having daptomycin-nonsusceptible isolates in the final year of the study. Infect Control Hosp Epidemiol 2018;39:226–228