Osteoporosis in liver disease: pathogenesis and management. (June 2016)

• Record Type: Journal Article
• Authors: Handzlik-Orlik, Gabriela; Holecki, Michał; Wilczyński, Krzysztof; Duława, Jan
• Is Part Of: Therapeutic advances in endocrinology and metabolism. Volume 7:Number 3(2016:Jun.)
• Page Start: 128
• Page End: 135
• Publication Date: 2016-06
• Subjects: bone metabolism -- cirrhosis -- hemochromatosis -- nonalcoholic fatty liver disease -- osteoporosis; Endocrine glands -- Diseases -- Treatment -- Periodicals; Metabolism -- Disorders -- Treatment -- Periodicals; Endocrine System Diseases -- therapy -- Periodicals; Metabolic Diseases -- therapy -- Periodicals; 616.4005
• DOI: 10.1177/2042018816641351
• Languages: English
• ISSNs: 2042-0188

Abstract

Osteoporosis affects a substantial proportion of patients with chronic liver disease. Pathologic fracture in osteoporosis significantly affects quality of life and life expectancy. By some estimates, 40% of patients with chronic liver disease may experience osteoporotic fracture. In this study we review the pathogenesis, diagnosis and treatment of specific liver disease entities and their relation to osteoporosis.