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Facile one pot multicomponent synthesis of novel 4-(benzofuran-2-yl)-2-(3-(aryl/heteryl)-5-(aryl/heteryl)-4, 5-dihydro-1H-pyrazol-1yl)thiazole derivatives. Issue 11 (3rd June 2018)
Record Type:
Journal Article
Title:
Facile one pot multicomponent synthesis of novel 4-(benzofuran-2-yl)-2-(3-(aryl/heteryl)-5-(aryl/heteryl)-4, 5-dihydro-1H-pyrazol-1yl)thiazole derivatives. Issue 11 (3rd June 2018)
Main Title:
Facile one pot multicomponent synthesis of novel 4-(benzofuran-2-yl)-2-(3-(aryl/heteryl)-5-(aryl/heteryl)-4, 5-dihydro-1H-pyrazol-1yl)thiazole derivatives
ABSTRACT: An efficient base catalyzed one pot multicomponent reaction of aryl/hetryl chalcones, thiosemicarbazide and 1-(benzofuran-2-yl)-2-bromoethan-1-one was developed to synthesize the novel 4-(benzofuran-2-yl)-2-(3-(aryl/heteryl)-5-(aryl/heteryl)-4, 5-dihydro-1 H -pyrazol-1yl)thiazole derivatives. GRAPHICAL ABSTRACT: