Opto-acousto-fluidic microscopy for three-dimensional label-free detection of droplets and cells in microchannels. Issue 9 (5th April 2018)

• Record Type: Journal Article
• Authors: Song, Chaolong; Jin, Tian; Yan, Ruopeng; Qi, Weizhi; Huang, Tianye; Ding, Huafeng; Tan, Say Hwa; Nguyen, Nam-Trung; Xi, Lei
• Is Part Of: Lab on a chip. Volume 18:Issue 9(2018)
• Page Start: 1292
• Page End: 1297
• Publication Date: 2018-04-05
• Subjects: Miniature electronic equipment -- Periodicals; Combinatorial chemistry -- Periodicals; Biotechnology -- Periodicals; 543.0813
• DOI: 10.1039/c8lc00106e
• Languages: English
• ISSNs: 1473-0197

Abstract

Abstract : We present here a novel opto-acousto-fluidic microscopy approach for three-dimensional label-free detection of droplets and cells in microfluidic networks. Abstract : This paper reports a novel method, opto-acousto-fluidic microscopy, for label-free detection of droplets and cells in microfluidic networks. Leveraging the optoacoustic effect, the microscopic system possesses capabilities of visualizing flowing droplets, analyzing droplet contents, and detecting cell populations encapsulated in droplets via the sensing of acoustic waves induced by the intrinsic light-absorbance of matter.