Asymmetric total syntheses of callistrilones B, G and J. Issue 9 (22nd March 2018)

• Record Type: Journal Article
• Authors: Hu, Li-Jun; Cheng, Min-Jing; Cao, Jia-Qing; Zhong, Li-Ping; Hu, Ya-Jian; Wang, Ying; Wang, Lei; Ye, Wen-Cai; Li, Chuang-Chuang
• Is Part Of: Organic chemistry frontiers. Volume 5:Issue 9(2018)
• Page Start: 1506
• Page End: 1510
• Publication Date: 2018-03-22
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/c8qo00130h
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : A highly concise approach for the first asymmetric and gram-scale total syntheses of callistrilones B, G and J is reported. Abstract : A very concise approach for the first asymmetric and scalable total syntheses of callistrilones B, G and J has been developed. These syntheses proceeded in only 3–4 steps from the commercially available (−)-α-phellandrene (8 ), without the need for protecting groups. The key feature of the syntheses was a biomimetic, diastereo- and regioselective oxidative [3 + 2] cycloaddition.