Systemic lupus erythematosus and myelofibrosis: A case report and revision of literature. (2018)

• Record Type: Journal Article
• Authors: Del Porto, F.; Tatarelli, C.; Di Napoli, A.; Proietta, M.
• Is Part Of: Leukemia research reports. Volume 9(2018)
• Page Start: 58
• Page End: 64
• Publication Date: 2018
• Subjects: Systemic lupus erythematosus -- Autoimmune myelofibrosis -- Blood cytopenia; Leukemia -- Periodicals; Lymphomas -- Periodicals; Multiple myeloma -- Periodicals; Leukemia -- Periodicals; Lymphoma -- Periodicals; Multiple Myeloma -- Periodicals; Hematologic Neoplasms -- Periodicals; Leukemia; Lymphomas; Multiple myeloma; Electronic journals; Periodicals; 616.9941905
• DOI: 10.1016/j.lrr.2018.04.004
• Languages: English
• ISSNs: 2213-0489

Abstract

Abstract: Blood cytopenia represents one of the diagnostic criteria for systemic lupus erythematosus (SLE) and may occur as the first symptom of the disease. Antibody-mediated peripheral destruction of blood cells is the main cause of cytopenia observed in patients affected by SLE, however, inflammatory anemia, nutritional deficiencies, immunosuppressive therapy and, more rarely, myelofibrosis (MF) have also been documented. In the literature, 45 cases of autoimmune MF (AIMF) and SLE have been previously reported. Here the 46 th case of a 43-year-old female with a SLE and an underhand cytopenia, with a review of the literature.