Solvent-free sonochemical kabachnic-fields reaction to synthesize some new α-aminophosphonates catalyzed by nano-BF3SiO2. (3rd June 2018)

• Record Type: Journal Article
• Authors: Ravikumar, D.; Mohan, S.; Subramanyam, Ch.; Rao, K. Prasada
• Is Part Of: Phosphorus, sulfur, and silicon and the related elements. Volume 193:Number 6(2018)
• Page Start: 400
• Page End: 407
• Publication Date: 2018-06-03
• Subjects: α-aminophosphonates -- ultrasonic irradiation -- nano-BF3SiO2 -- antioxidant activity; Sulfur compounds -- Periodicals; Organosulfur compounds -- Periodicals; Phosphorus compounds -- Periodicals; Organophosphorus compounds -- Periodicals; Silicon compounds -- Periodicals; Organosilicon compounds -- Periodicals; 546
• DOI: 10.1080/10426507.2018.1424163
• Languages: English
• ISSNs: 1042-6507

Abstract

GRAPHICAL ABSTRACT: ABSTRACT: To obtain a rapid, efficient synthesis of some new α-aminophosphonates, ultrasonic irradiation has been applied to the reaction mixtures containing amine, aromatic or heteroaromatic aldehydes and triethyl phosphite. The Kabachnik-Fields reaction was performed by using nano-BF3 SiO2 as a recyclable catalyst under solvent free conditions. Key advantages of this procedure consist in the eco-friendly and highly efficient reaction conditions, high yields, an easy work-up procedure, short reaction times and solvent free conditions. All title compounds were characterized by spectral and elemental analysis. They were further screened for their in vitro antioxidant activity by the DPPH, O 2− and NO methods. The majority of the title compounds showed good antioxidant activity when compared with the standard antioxidants.