Lack of Prominent Cognitive Regression in the Long-term Outcome of Patients Having Electrical Status Epilepticus During Sleep With Different Types of Epilepsy Syndromes. (July 2015)

• Record Type: Journal Article
• Authors: Bebek, Nerses; Gürses, Candan; Baykan, Betül; Gökyiğit, Aysen
• Is Part Of: Clinical EEG and neuroscience. Volume 46:Number 3(2015:Jul.)
• Page Start: 235
• Page End: 242
• Publication Date: 2015-07
• Subjects: ESES -- CSWS -- long-term follow-up -- outcome -- epileptic syndromes; Electroencephalography -- Periodicals; Neurosciences -- Periodicals; 616.8047547
• DOI: 10.1177/1550059413514388
• Languages: English
• ISSNs: 1550-0594

Abstract

The purpose was to document 4 patients with different epilepsy syndromes, showing electrical status epilepticus during sleep (ESES), without marked cognitive and behavioral regression in the long-term follow-up. The mean age at onset of seizures was 8 years. Absences, myoclonic, focal motor, or generalized tonic - clonic seizures and drop attacks were the prominent seizure types. The neurological examination and neuroimaging findings revealed no abnormality. Focal epileptiform electroencephalographic (EEG) activity was seen in 3 cases, whereas generalized photosensitive epileptic discharges were detected in 1 patient with juvenile myoclonic epilepsy. Neuropsychological evaluations of all cases were within the normal range, and deterioration in mental status was not observed during their mean follow-up duration of 14 years. Our data support the view that ESES can emerge along with different types of childhood epilepsy syndromes, including idiopathic generalized epilepsies, and may not always be a poor prognostic factor.