Four key questions surrounding thrombolytic therapy for submassive pulmonary embolism. (February 2016)

• Record Type: Journal Article
• Authors: Sista, Akhilesh K; Horowitz, James M; Goldhaber, Samuel Z
• Is Part Of: Vascular medicine. Volume 21:Number 1(2016:Feb.)
• Page Start: 47
• Page End: 52
• Publication Date: 2016-02
• Subjects: catheter-directed therapy -- pulmonary embolism -- submassive PE -- thrombolysis; Blood-vessels -- Diseases -- Periodicals; Peripheral vascular diseases -- Periodicals; Vascular Diseases -- Periodicals; Vaisseaux sanguins -- Maladies -- Périodiques; Maladies vasculaires périphériques -- Périodiques; 616.13
• DOI: 10.1177/1358863X15614388
• Languages: English
• ISSNs: 1358-863X

Abstract

Submassive pulmonary embolism (PE) remains a vexing entity, and the appropriate use of thrombolytic therapy for this subgroup continues to be actively debated. Catheter-directed thrombolysis has shown efficacy for submassive PE and is gaining momentum because of theoretically improved safety. This review poses and responds to four questions that explore the complex issues surrounding optimal therapy of submassive PE.