The contemporary management of primary urethral carcinoma. (November 2015)

• Record Type: Journal Article
• Authors: Blick, Christopher; Sahdev, Varun; Mitra, Anita; Nigam, Raj; Muneer, Asif
• Is Part Of: Journal of clinical urology. Volume 8:Number 6(2015:Nov.)
• Page Start: 412
• Page End: 419
• Publication Date: 2015-11
• Subjects: Cancer therapy -- human papilloma virus -- review -- squamous cell carcinoma -- surgery -- urethral cancer; Genitourinary organs -- Surgery -- Periodicals; Genitourinary organs -- Diseases -- Periodicals; Urology -- Periodicals; 616.6005
• DOI: 10.1177/2051415815584129
• Languages: English
• ISSNs: 2051-4158

Abstract

Primary urethral cancer is a rare malignancy; the most common histological subtype is squamous cell carcinoma. The aetiology of this cancer is similar to penile cancer and the human papilloma virus (HPV) is thought to be an important factor in tumourigenesis. Surgery with or without chemoradiotherapy is the accepted treatment for primary urethral cancer. Current practice supports penile-sparing surgery, to maximise functional and psychological outcomes. We have reviewed the literature to summarise the pathogenesis and management of primary urethral cancer.