Carbapenem resistance: overview of the problem and future perspectives. (February 2016)

• Record Type: Journal Article
• Authors: Meletis, Georgios
• Is Part Of: Therapeutic advances in infectious disease. Volume 3:Number 1(2016:Feb.)
• Page Start: 15
• Page End: 21
• Publication Date: 2016-02
• Subjects: antibiotic resistance -- carbapenemases -- carbapenems; Communicable diseases -- Treatment -- Periodicals; Infection -- Treatment -- Periodicals; 616.905
• DOI: 10.1177/2049936115621709
• Languages: English
• ISSNs: 2049-9361

Abstract

Carbapenem resistance, mainly among Gram-negative pathogens, is an ongoing public-health problem of global dimensions. This type of antimicrobial resistance, especially when mediated by transferable carbapenemase-encoding genes, is spreading rapidly causing serious outbreaks and dramatically limiting treatment options. In this article, important key points related to carbapenem resistance are reviewed and future perspectives are discussed.