Association of Attention Deficit Disorder With Bedside Anti-saccades in Survivors of Childhood Leukemia. (February 2016)

• Record Type: Journal Article
• Authors: Khan, Raja B.; Hudson, Melissa M.; Ness, Kirsten K.; Liang, Zhu; Srivastava, Deokumar; Krull, Kevin R.
• Is Part Of: Journal of child neurology. Volume 31:Number 2(2016:Feb.)
• Page Start: 131
• Page End: 133
• Publication Date: 2016-02
• Subjects: attention deficit disorder -- childhood -- acute lymphoblastic leukemia -- anti-saccades -- soft signs; Nervous system -- Diseases -- Periodicals; 618.928
• DOI: 10.1177/0883073815583689
• Languages: English
• ISSNs: 0883-0738

Abstract

Impaired attention is well recognized in childhood cancer survivors. We prospectively evaluated 162 long-term survivors of childhood acute lymphoblastic leukemia to study an association between presence of neurologic soft signs as measured by Zurich Neuromotor Scale, bedside evaluation of anti-saccades, and attention deficit disorder. Attention deficit disorder was recognized in 10.5% of the study cohort. We did not find an association of attention deficit with presence of any soft sign. However, there was an association between presence of abnormal anti-saccades and attention deficit ( P = .04). These results will require further validation and if confirmed may introduce a quick bedside method of assessing impaired attention in cancer survivors.