Biorefinery of olive leaves to produce dry oleuropein aglycone: Use of homemade ceramic capillary biocatalytic membranes in a multiphase system. (10th August 2018)

• Record Type: Journal Article
• Authors: Ranieri, Giuseppe; Mazzei, Rosalinda; Poerio, Teresa; Bazzarelli, Fabio; Wu, Zhentao; Li, Kang; Giorno, Lidietta
• Is Part Of: Chemical engineering science. Volume 185(2018)
• Page Start: 149
• Page End: 156
• Publication Date: 2018-08-10
• Subjects: Oleuropein aglycone -- 3, 4-DHPEA-EA -- Multiphase membrane reactor -- Capillary ceramic membranes -- Phytotherapic production -- Waste valorization -- Green technology; Chemical engineering -- Periodicals; Génie chimique -- Périodiques; Chemical engineering; Periodicals; Electronic journals; 660
• DOI: 10.1016/j.ces.2018.03.053
• Languages: English
• ISSNs: 0009-2509

Abstract

Graphical abstract: Highlights: Hydrophobic oleuropein aglycone is an antioxidant not commercially available. It can be continuously produced from olive leaves by an intensified membrane process. Multiphase biocatalytic membrane reactor allowed produce/extract the aglycone. An unstable water-in-oil emulsion produced in the permeate allowed the extraction. Enriched powder of oleuropein aglycone can be produced after solvent evaporation. Abstract: Oleuropein aglycone is an important antioxidant compound produced during oleuropein hydrolysis, not yet commercially available. Its production from renewable material by green processes is a challenge because it permits waste re-use and low environmental impact. In this work, homemade asymmetric capillary ceramic membranes were used to develop biocatalytic membranes, which were further used to produce oleuropein aglycone from olive leaves and/or commercial oleuropein. Results indicated that the biocatalytic system (containing covalently immobilized β-glucosidase) promotes the hydrolysis of oleuropein in both monophase and multiphase processes. Furthermore, the multiphase biocatalytic system enables the extraction of the hydrophobic oleuropein aglycone in an organic phase, before its rearrangement in water. This was achieved by the production, of an unstable water-in-oil emulsion (permeate side), on the basis of membrane emulsification process. The intensified biocatalytic/extractor system allowed taking shelter the hydrophobic compound in the organic phase with good efficiency (90%), protecting it from rearrangement.