Activity restriction and risk of preterm delivery*. (18th August 2018)

• Record Type: Journal Article
• Authors: Levin, Heather I.; Sciscione, Anthony; Ananth, Cande V.; Drassinower, Daphnie; Obican, Sarah G.; Wapner, Ronald J.
• Is Part Of: Journal of maternal-fetal & neonatal medicine. Volume 31:Number 16(2018)
• Page Start: 2136
• Page End: 2140
• Publication Date: 2018-08-18
• Subjects: Activity restriction -- bed rest -- preterm birth -- spontaneous preterm birth; Obstetrics -- Periodicals; Perinatology -- Periodicals; Infants (Newborn) -- Diseases -- Periodicals; Neonatology -- Periodicals; 618.2
• DOI: 10.1080/14767058.2017.1337738
• Languages: English
• ISSNs: 1476-7058

Abstract

Abstract: Purpose: We sought to determine whether activity restriction (AR) in a cohort of women at high risk for preterm delivery is associated with the risk of preterm delivery. Materials and methods: This is a secondary analysis of the Maternal-Fetal Medicine Units MFMU's Preterm Prediction Study; a multicenter prospective cohort study designed to identify risk factors of preterm birth (PTB). The study group consisted of women with a singleton gestation that at their first study visit (23–24 weeks) had at least one of the following criteria: patient reported contractions, severe back pain, a cervical length <15 mm, spotting, protruding membranes, or positive fetal fibronectin. Women were assessed for AR at a 27- to 29-week study visit. Associations between AR and preterm delivery (<37 weeks) were examined through logistic regression models before and after adjustment for confounders. Results: Of the 1086 women that met the inclusion criteria, 16.5% ( n = 179) delivered preterm. In this cohort, 9.7% ( n = 105) of women were recommended AR, with 37.1% ( n = 39) having a PTB. In the group not recommended AR ( n = 981), 14.3% ( n = 140) delivered preterm. Conclusion: In this cohort of women at high risk for PTB, activity restriction was associated with an increased risk of PTB. The use of AR in this population should be discouraged.