Effectiveness of bronchial thermoplasty in severe asthma in 'real life' patients compared with those recruited to clinical trials in the same centre. (December 2015)

• Record Type: Journal Article
• Authors: Bicknell, Stephen; Chaudhuri, Rekha; Lee, Nicola; Shepherd, Malcolm; Spears, Mark; Pitman, Nick; Cameron, Euan; Cowan, Douglas; Nixon, Julie; Thompson, Joyce; McSharry, Charles; Thomson, Neil C.
• Is Part Of: Therapeutic advances in respiratory disease. Volume 9:Number 6(2015:Dec.)
• Page Start: 267
• Page End: 271
• Publication Date: 2015-12
• Subjects: asthma -- bronchial thermoplasty -- bronchoscopy; Respiratory organs -- Diseases -- Periodicals; Respiratory agents -- Periodicals; Pulmonary pharmacology -- Periodicals; Respiratory Tract Diseases -- Periodicals; Respiratory System Agents -- therapeutic use -- Periodicals; Respiratory Tract Diseases -- drug therapy -- Periodicals; Lung Diseases -- drug therapy -- Periodicals; Appareil respiratoire -- Maladies -- Traitement -- Périodiques; Agents respiratoires -- Périodiques; Pharmacologie pulmonaire -- Périodiques; 616.2005
• DOI: 10.1177/1753465815601332
• Languages: English
• ISSNs: 1753-4658

Abstract

Published information on the effectiveness of bronchial thermoplasty (BT) for severe asthma in 'real life' patients is limited. We compared safety and efficacy outcomes 12 months post procedure in 10 clinic patients and 15 patients recruited to clinical trials of BT at the same centre. Baseline asthma severity was greater in the clinic group. Adverse events were similar. Clinical improvements occurred in 50% of the clinic patients compared with 73% of the research patients.