Acute Kidney Injury in Cardiac Surgery and Cardiac Intensive Care. (December 2015)

• Record Type: Journal Article
• Authors: Lau, Gary; Wald, Ron; Sladen, Robert; Mazer, C. David
• Other Names: Lighthall Geoffrey K. guest-editor.
• Is Part Of: Seminars in cardiothoracic and vascular anesthesia. Volume 19:Number 4(2015:Dec.)
• Page Start: 270
• Page End: 287
• Publication Date: 2015-12
• Subjects: cardiopulmonary bypass -- cardiac anesthesia -- coagulation -- hemostasis; Cardiovascular system -- Surgery -- Methods -- Periodicals; Chest -- Surgery -- Methods -- Periodicals; Anesthesia -- Periodicals; Anesthetics -- Periodicals; Anesthesia -- Periodicals; Anesthetics -- Periodicals; Cardiovascular Surgical Procedures -- methods -- Periodicals; Thoracic Surgical Procedures -- methods -- Periodicals; 617.96
• DOI: 10.1177/1089253215593177
• Languages: English
• ISSNs: 1089-2532

Abstract

Acute kidney injury (AKI) is a serious postoperative complication following cardiac surgery. Despite the incidence of AKI requiring temporary renal replacement therapy being low, it is nonetheless associated with high morbidity and mortality. Therefore, preventing AKI associated with cardiac surgery can dramatically improve outcomes in these patients. The pathogenesis of AKI is multifactorial and many attempts to prevent or treat renal injury have been met with limited success. In this article, we will discuss the incidence and risk factors for cardiac surgery associated AKI, including the pathophysiology, potential biomarkers of injury, and treatment modalities.