PATHWAY-2 and -3: Potassium-Sparing Diuretics Safe and Effective for Resistant Hypertension. Issue 28 (29th October 2015)

• Record Type: Journal Article
• Authors: Zarifyan, Alla
• Other Names: Williams Bryan presenter.; Brown Morris J. presenter.
• Is Part Of: MD conference express. Volume 15:Issue 28(2015)
• Page Start: 12
• Page End: 13
• Publication Date: 2015-10-29
• Subjects: amiloride -- bisoprolol -- high blood pressure -- diabetes -- doxazosin -- HCTZ -- hydrochlorothiazide -- potassium -- spironolactone -- PATHWAY-2 -- PATHWAY-3; Medicine -- Congresses; 610
• DOI: 10.1177/1559897715611371
• Languages: English
• ISSNs: 1559-8977

Abstract

PATHWAY-2 and PATHWAY-3 demonstrated that potassium-sparing diuretics are safe and effective for the treatment of hypertension. Spironolactone was significantly more effective in controlling resistant hypertension than doxazosin or bisoprolol, whereas the amiloride/HCTZ combination neutralized the undesirable changes in blood glucose and potassium while significantly lowering blood pressure.