Layered double hydroxide-enhanced luminescence in a Fenton-like system for selective sensing of cobalt in Hela cells. (25th September 2017)

• Record Type: Journal Article
• Authors: Yu, Mei; Yuan, Zhiqin; Lu, Chao
• Is Part Of: Methods and applications in fluorescence. Volume 5:Number 3(2017:Sep.)
• Publication Date: 2017-09-25
• Subjects: layered double hydroxides (LDHs) -- chemiluminescence (CL) -- cobalt -- biosensing; Fluorescence spectroscopy -- Periodicals; Fluorescence -- Periodicals; Spectrometry, Fluorescence -- Periodicals; Fluorescence -- Periodicals; Fluorescence; Fluorescence spectroscopy; Periodicals; 535.352
• DOI: 10.1088/2050-6120/aa7762
• Languages: English
• ISSNs: 2050-6120

Abstract

Abstract: This work presented a facile and eco-friendly method for the determination of cobalt ions (Co(II)) in living cells based on layered double hydroxides (Mg-Al CO3 -LDHs) enhanced chemiluminescence (CL) emission of a Co(II)-hydrogen peroxide-sodium hydroxide system. The enhanced CL emission was attributed to the large specific surface area of Mg-Al CO3 -LDHs, which facilitates the generation of an excited-stated intermediate. The proposed method displayed high selectivity toward Co(II) over other metal ions. Under the optimal conditions, the increased CL intensity showed a linear response versus Co(II) concentration in the range of 5.0–1000 nM with a detection limit of 3.7 nM (S/N = 3). The relative standard deviation for nine repeated measurements of 100 nM Co(II) was 3.2%. Furthermore, the proposed method was successfully applied to detect Co(II) in living cell samples, and the results were agreed with those obtained by the standard ICP-MS method.