Malnutrition and Cachexia in Heart Failure. (29th January 2015)

• Record Type: Journal Article
• Authors: Rahman, Adam; Jafry, Syed; Jeejeebhoy, Khursheed; Nagpal, A. Dave; Pisani, Barbara; Agarwala, Ravi
• Is Part Of: JPEN, Journal of parenteral and enteral nutrition. Volume 40:Number 4(2016)
• Page Start: 475
• Page End: 486
• Publication Date: 2015-01-29
• Subjects: internal medicine -- nutrition -- nutrition assessment -- minerals/trace elements -- proteins -- vitamins -- nutrition support practice -- outcomes research/quality -- cardiac disease -- research and diseases -- critical care -- organ transplantation; Parenteral feeding -- Periodicals; Enteral feeding -- Periodicals; 615.85484
• DOI: 10.1177/0148607114566854
• Languages: English
• ISSNs: 0148-6071

Abstract

Abstract : Heart failure is a growing public health concern. Advanced heart failure is frequently associated with severe muscle wasting, termed cardiac cachexia . This process is driven by systemic inflammation and tumor necrosis factor in a manner common to other forms of disease‐related wasting seen with cancer or human immunodeficiency virus. A variable degree of malnutrition is often superimposed from poor nutrient intake. Cardiac cachexia significantly decreases quality of life and survival in patients with heart failure. This review outlines the evaluation of nutrition status in heart failure, explores the pathophysiology of cardiac cachexia, and discusses therapeutic interventions targeting wasting in these patients.